Before You Start

Rebecca & Billy — Survival Strategy

This guide covers Rebecca Chambers and Billy Coen's full route through Resident Evil Zero, from the Ecliptic Express train to the final confrontation beneath the Umbrella Training Facility. Unlike most Resident Evil games, you control both characters throughout — splitting them up to solve two-person puzzles, or keeping them together for safety in a fight — and there's no item box to fall back on, so managing what you carry and where you leave the rest matters as much as managing ammo.

Difficulty:
(Challenging / Puzzle-Heavy)
Key Points
  • Inventory: 6 slots each, no item boxes — anything you drop stays exactly where you left it
  • Core Mechanic: Partner Zapping — split Rebecca and Billy up or keep them together at will
  • Primary Threats: Zombies, Umbrella experiments, and two fights against the Prototype Tyrant
Recommendations
  • There is no item box in this game — pick one or two rooms near each save point and use them as your personal stash.
  • Get comfortable switching control between characters and setting your idle partner to Wait so they stop wasting ammo.
  • Save Magnum rounds, Grenade Launcher rounds, and Molotov Cocktails for the Prototype Tyrant and Queen Leech fights — regular firearms struggle against both.
  • Search every corpse you come across; several key items and ammo caches are hidden on bodies rather than in plain sight.

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