Enemies

The mansion's most common threat, and the reason you carry a Kerosene Canteen everywhere — any zombie left unburned eventually comes back as a much deadlier Crimson Head.

A regular zombie's second life. Faster, far tougher, and capable of lunging at you, Crimson Heads exist purely to punish skipping the Kerosene Canteen — burn bodies as you go and you'll rarely see one.

Fast, aggressive dogs that often ambush through windows or in packs. One solid hit knocks them down — wait for them to stand back up rather than wasting a second shot immediately.

Regular-sized spiders show up a few times and are easy to simply walk around rather than fight.

Fast, reptilian bio-weapons that start showing up once you've made progress in the guesthouse and aquarium. Their jumping claw attack can be lethal if your health is already low.

Grafted human-insect hybrids that ambush from the lab's vents and ceiling. The Magnum handles them cleanly; save it for these fights if you can.

Two smaller sharks patrol the flooded aquarium halls. They're manageable, but simply avoiding them while the water's still up is the better use of your resources.

Fought twice — first as a scripted encounter in the attic (where Richard may sacrifice himself against it on Jill's path), then again for real in the Library, where either the Shotgun or Magnum brings it down.

A massive shark stranded once the aquarium's tanks are drained. Rather than fight it directly, pull the generator lever to electrocute it and safely retrieve the key it's guarding.

A mutated, carnivorous plant that's overrun the guesthouse gallery. Jill can weaken it with V-Jolt chemical solution beforehand, turning the fight into a formality; Chris, lacking any chemistry knowledge in this remake, has to fight it head-on.

A boss-sized spider guarding the mine passages. A few Shotgun blasts put it down for good.

A tortured, immortal experiment who stalks you through several earlier areas purely to unsettle you — running is always the right call until the Altar, where knocking down the room's four pillars finally ends her.

Umbrella's ultimate bioweapon, unleashed by Wesker himself. Fought once in the lab's containment room and again, further mutated, on the helipad — where a Rocket Launcher from Brad is the only thing that finishes it for good.